The evolution of eccrine sweat gland research towards developing a model for human sweat gland function

Eccrine sweat gland carcinoma.

The differential diagnosis among the most frequent skin tumors, base-cell carcinoma and squamous-cell carcinoma, and the rare types, the sweat gland carcinomas, is fundamental for the early diagnosis and prognosis of a patient. These are classified as eccrine and apocrine, and the eccrine is the most common type. The eccrine sweat glands are most abundant in the palms of the hands and the feet ...

Sweat induction from an isolated eccrine sweat gland.

SAW, KENZO. Sweat induction from an isolated eccrine sweat gland. Am. J. Physiol. 225(5) : 1147-l 152. 1973.-A method has been developed for in vitro induction of sweating from an isolated monkey-palm eccrine sweat gland. The validity of the new methodology is shown in the following results. MecholyLinduced sweating was completely inhibited by atropine and by cooling the incubation medium to 4 ...

The Junctional Complex Associated Body of Human Eccrine Sweat Gland

The junctional complex connecting epithelial cells at their luminal pole consists of a complex of highly specialized structures which provide attachment (5-7) and communication (10) between cells . This junctional complex includes the zonula occludens, the underlying zonula adherens and, at intervals, the subjacent macula adherens or desmosome. Although this complex of fine structures occurs ve...

Human eccrine sweat gland cells can reconstitute a stratified epidermis.

Eccrine sweat glands are generally considered to be a possible epidermal stem cell source. Here we compared the multilayered epithelia formed by epidermal keratinocytes and those formed by eccrine sweat gland cells. We demonstrated both in vitro and in vivo the capability of human eccrine sweat gland cells to form a stratified interfollicular epidermis substitute on collagen hydrogels. This is ...

Sodium Secretion and Reabsorption in the Human Eccrine Sweat Gland.